Garcia stated the evacuation mission was “accomplished” after two days of moving 125 people from 23 countries.
The vessel is carrying 25 crew, two medical staff, and the body of a German passenger who died during the cruise.
It is expected to arrive in Rotterdam on 17 May for disinfection.
The hantavirus strain linked to the outbreak is the Andes strain, the only known variant capable of human-to-human transmission.
While the MV Hondius left Argentina on 1 April, the WHO believes the first infection occurred before the voyage, followed by transmission on board.
However, Argentine officials have questioned whether the outbreak originated in Ushuaia.
Health authorities in several countries are now tracking passengers and anyone who may have come into contact with them to prevent further spread.
